Brain Powerd(1998)

Brain Powerd is a sci-fi anime series set on a ravaged future Earth where a mysterious alien spacecraft called Orphan has been discovered. Researchers hunt across the planet for Orphan's disc plates, piloting massive mecha known as Antibodies to resurrect the ship—an act that would annihilate all life on the planet. Yu Isami and Hime Utsumiya emerge as humanity's last hope, commanding an advanced Antibody mecha called Brain Powerd to thwart the Orphan conspiracy and prevent extinction. The series blends mecha action with high-stakes survival drama as the protagonists race against time to stop a cataclysm that could erase civilization.